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Critical Thinking in Critical Care Medicine


BICAR-ICU trial: in a subgroup with severe acidemia and severe Acute Kidney Injury a bicarbonate infusion reduces need for renal replacement therapy and potentially mortality at 28 days.
Sodium bicarbonate therapy for patients with severe metabolic acidaemia in the intensive care unit (BICAR-ICU): a multicentre,...

David Goldenberg, DO
Jan 24 min read
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STARRT - AKI trial. Harm and unnecessary Renal Replacement Therapy (RRT) when RRT is started early in the ICU.
Critical Appraisal of the Starrt - AKI trial for early renal replacement in the ICU

Peter Tofts, MD
Oct 22, 20243 min read
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